top of page

  • Habicher, J.; Sanvido, I.; Bühler, A.; Sartori, S.; Piccoli, G.; Carl, M. (2024). The risk genes for neuropsychiatric disorders negr1 and opcml are expressed throughout zebrafish brain development. Genes, 15:363. https://doi.org/10.3390/genes15030363.

  • Agostini, C., Bühler, A., Antico Calderone, A., Aadepu, N., Herder, C., Loosli, F. and Carl, M. (2022). Conserved and diverged asymmetric gene expression in the brain of teleosts. Frontiers in Cell and Developmental Biology, doi: 10.3389/fcell.2022.1005776.

  • Bühler, A. and Carl, M. (2021). Zebrafish tools for deciphering habenular network-linked mental disorders. Biomolecules, 11(2):324. (invited review)

  • Albadri, S., Armant, O., Aljand-Geschwill, T., Del Bene, F., Carl, M., Strähle, U., Poggi, L. (2020). Expression of a Barhl1a reporter in subsets of retinal ganglion cells and commissural neurons of the developing zebrafish brain. Scientific Reports, 10(1):8814.

  • Guglielmi, L., Bühler, A., Moro, E., Argenton, F., Poggi, L. and Carl, M. (2020). Temporal control of Wnt signaling is required for habenular neuron diversity and brain asymmetry (2020). Development, 147(6):dev.182865.

  • Imle, R., Wang, B.-T., Stützenberger, N., Birkenhagen, J., Tandon, A., Carl, M., Himmelreich, N., Thiel, C., Gröne, H.-J., Poschet, G., Völkers, M., Gülow, K., Schröder, A., Carillo, S., Mittermayr, S., Bones, Jo., Kaminski, M.M., Kölker, S., Sauer, S.W. (2019). ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing. Scientific Reports, 9(1):14248.

  • Breuer, M., Guglielmi, L., Zielonka, M., Hemberger, V., Kölker, S., Okun, J.G., Hoffmann, G.F., Carl, M. #, Sauer, S.W. #, Opladen, T. # (2019). Qdpr homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis. Plos One, 14(4):e0215162. (#equal contribution)

 

  • Zielonka, M., Probst, J., Carl, M., Hoffmann, G.F., Kölker, S., Okun,, J.G. (2019). Bioenergetic dysfunction in a zebrafish model of acute hyperammonemic decompensation. Experimental Neurology, 314:91-99.

 

  • Poggi, L., Casarosa, S., Carl, M. (2018). An eye on the Wnt inhibitory factor Wif1. Frontiers in Cell and Developmental Biology, 6:167. (invited review)

 

  • Roussigné, M., Wei, L., Tsingos, E., Kuchling, F., Alkobtawi, M., Tsalavouta, M., Witbrodt, J.W., Carl, M., Blader, P., Wilson, S.W. (2018). Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signalling activity in leading cells. Proceedings of the National Academy of Sciences USA, 115(42):E9812-E9821.

 

  • Zielonka, M., Breuer, M., Okun, J. G., Carl, M., Hoffmann, G. F., Kölker, S. (2018). Pharmacologic rescue of hyperammonemia-induced toxicity in zebrafish by inhibition of ornithine aminotransferase. Plos One, 13(9):e0203707.

 

  • Dimitrov, B., Himmelreich, N., Hipgrave Ederveen, A.L., Lüchtenborg, C., Okun, J.O., Breuer, M., Hutter, A.-M., Carl, M., Guglielmi, L., Hellwig, A., Thiemann, K.C., Jost, M., Peters, V., Staufner, C., Hoffmann, G.F., Hackenberg, A., Paramasivam, N., Wiemann, S., Eils, R., Schlesner, M., Strahl, S., Brügger, B., Wuhrer, M., Korenke, G.C., and Thiel, C. (2018). Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolism as additional symptoms in a new patient with ATP6AP1-CDG. Molecular Genetics and Metabolism, 123(3):364-374.

 

  • Choi, J.-H., Jeong, Y.-M., Kim, S., Lee, B., Ariyasiri, K., Kim, H.-T., Jung, S.-H., Seung, Hwang, K.-S., Choi, T.-I., Park, C.O., Huh, W.-H., Carl, M., Rosenfeld, J.A., Raskin, S., Ma, A., Gecz, J., Kim, H.-G., Kim, J.-S., Shin, H.-C., Park, D.-S., Gerlai, R., Jamieson, B.B., Kim, J.S., Iremonger, K.J., Lee, S.H., Shin, H.-S., Kim, C.-H. (2018). Targeted knockout of a chemokine-like gene increases anxiety and fear responses. Proceedings of the National Academy of Sciences USA, 115(5):E1041-E1050.

 

  • Cepero Malo, M., Duchemin, A.-L., Guglielmi, L., Patzel, E., Sel, S., Auffarth, G.U., Carl, M., and Poggi, L. (2017). The zebrafish Anillin-eGFP reporter marks late dividing retinal precursors and stem cells entering neuronal lineages. Plos One, 12(1):e0170356.

 

  • Beretta, C.A., Dross, N., Guglielmi, L., Bankhead, P., Soulika, M., Gutierrez-Triana, J.A., Paolini, A., Poggi, L., Falk, J., Ryu, S., Kapsimali, M., Engel, U., Carl, M. (2017). Early commissural diencephalic neurons control habenular axon extension and targeting. Current Biology, 27:270-278.

 

  • Kopajtich, R., Murayama, K., Janecke, A.R., Haack, T.B., Breuer, M., Knisely, A.S., Harting, I., Ohashi, T., Okazaki, Y., Watanabe, D., Tokuzawa, Y., Kotzaeridou, U., Kölker, S., Sauer, S., Carl, M., Straub, S., Entenmann, A., Gizewski, E., Feichtinger, R.G., Mayr, J.A., Lackner, K., Strom, T.M., Meitinger, T., Müller, T., Ohtake, A., Hoffmann, G.F., Prokisch, H., Staufner, C. (2016). Biallelic mutations in IARS, encoding cytosolic isoleucyl-tRNA synthetase, cause growth retardation with prenatal onset, intellectual disability, muscular hypotonia, and infantile hepatopathy. American Journal of Human Genetics, 99:414-422.

 

  • Beretta, C.A., Dross, N., Engel, U., and Carl, M. (2016). Tracking cells in GFP-transgenic zebrafish using the photoconvertible PSmOrange system. J. Vis. Exp. (108), e53604.

 

  • Hüsken, U., Stickney, H.L., Gestri, G., Bianco, I.H., Faro, A., Young, R.M., Roussigne, M., Hawkins, T.A., Beretta, C.A., Brinkmann, I., Paolini A., Jacinto, R., Albadri, S., Dreosti, E., Tsalavouta, M., Schwarz, Q., Cavodeassi, F., Barth, A.K., Wen, L., Zhang, B., Blader, P., Yaksi, E., Poggi, L., Zigman, M., Lin, S., Wilson, S.W., and Carl, M. (2014). Tcf7l2 is required for left-right asymmetric differentiation of habenular neurons. Current Biology 24(19):2217-2227. (Featured in Biomedical Picture of the Day – BPoD)

 

  • Dross, N., Beretta, C.A., Bankhead, P., Carl, M., and Engel, U. (2014). Zebrafish Brain Development Monitored by Long-Term in Vivo Microscopy: A Comparison Between Laser Scanning Confocal and 2-Photon Microscopy. Book Title: Laser Scanning Microscopy and Quantitative Image Analysis of Neuronal Tissue. Springer Science.

 

  • Dreosti, E., Llopis, N.V., Carl, M., Yaksi E., and Wilson, S.W. (2014). Left/right asymmetry is required for the habenulae to respond to both visual and olfactory stimuli. Current Biology 24(4):440-445.

 

  • Mwafi, N., Beretta, C.A., Paolini, A., and Carl, M. (2014). Divergent Wnt8a gene expression in teleosts. Plos One 9(1):e85303.

 

  • Beretta, C.A., Dross, N., Bankhead, P., and Carl, M. (2013). The ventral habenulae in zebrafish develop in prosomere 2 dependent on Tcf7l2 function, Neural Development 8(1):19. (Image highlight October 2013)

 

  • Demir, K., Kirsch, N., Beretta, C.A., Erdmann, G., Ingelfinger, D., Moro, E., Argenton, F., Carl, M., Niehrs, C., and Boutros, M. (2013). RAB8B is required for activity and caveolar endocytosis of LRP6. Cell Reports 4(6):1224-1234.

 

  • Hüsken, U. and Carl, M. (2013). The Wnt/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. Mech. Dev. 130: 330-335. (invited review)

 

  • McNabb, A., Scott, K., von Ochsenstein, E., Seufert, K. and Carl, M. (2012). Don’t be afraid to set up your fish facility. Zebrafish 9(3): 120-125.

 

  • Beretta, C.A., Dross, N., Guiterrez-Triana, J.A., Ryu, S. and Carl, M. (2012). Habenula circuit development: past, present, and future. Frontiers in Neuroscience 6:51. (invited review)

 

  • Berns, N., Woichansky, I., Kraft, N., Hüsken, U., Carl, M. and Riechmann, V. (2012). „Vacuum-assisted staining“: a simple and efficient method for screening Drosophila. Dev. Genes Evol. 222: 113-118.

 

  • Beretta, C.A., Brinkmann, I. and Carl, M. (2011). All four zebrafish Wnt7 genes are expressed during early brain development. Gene Expression Patterns 11: 277-284.

 

  • Wilkinson, C.J., Carl, M. and Harris, W.A. (2009). Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. BMC Cell Biology 10:17.

 

  • Bianco, I.H., Carl, M., Russell, C., Clark, J. and Wilson, S.W. (2008). Brain asymmetry is encoded at the level of axon terminal morphology. Neural Development 3: 9. (Shortlisted for the 2008 Biomed Central Biology Prize)

 

  • Carl, M., Bianco, I.H., Bajoghli, B., Aghaallaei, N., Czerny, T., and Wilson, S.W. (2007). Wnt/Axin1/b-catenin signaling regulates asymmetric nodal activation, elaboration, and concordance of CNS asymmetries. Neuron 55(3): 393-405. (highlighted by A. Sagasti; Minireview same issue)

 

  • Yokoi, H., Shimada, A., Carl, M., Takashima, S., Kobayashi, D., Narita, T., Jindo, T., Kimura, T., Kitagawa, T., Kage, T., Sawada, A., Naruse, K., Asakawa, S., Shimizu, N., Mitani, H., Shima, A., Tsutsumi, M., Hori, H., Wittbrodt, J., Saga, Y., Ishikawa, Y., Araki, K., and Takeda, H. (2007). Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships. Dev. Biol. 304(1): 326-337.

 

  • Hochmann, S., Aghaallaei, N., Bajoghli, B., Soroldoni, D., Carl, M., and Czerny, T. (2007). Expression of marker genes during early ear development in medaka. Gene Expression Patterns 7(3): 355-362.

 

  • Gestri, G., Carl, M., Appolloni, I., Wilson, S.W., Barsacchi, G., and Andreazzoli, M. (2005). Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expression. Development 132(10): 2401-2413.

 

  • Furutani-Seiki, M., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Yoda, H., Deguchi, T., Hirose, Y., Yasuoka, A., Henrich, T., Watanabe, T., Iwanami, N., Kitagawa, D., Saito, K., Asaka, S., Osakada, M., Kunimatsu, S., Momoi, A., Elmasri, H., Winkler, C., Ramialison, M., Loosli, F., Quiring, R., Carl, M., Grabher, C., Winkler, S., Del Bene, F., Shinomiya, A., Kota, Y., Yamanaka, T., Okamoto, Y., Takahashi, K., Todo, T., Abe, K., Takahama, Y., Tanaka, M., Mitani, H., Katada, T., Nishina, H., Nakajima, N., Wittbrodt, J. and Kondoh, H. (2004). A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mech. Dev. 121, 647- 658.

 

  • Elmasri, H., Winkler, C., Liedtke, D., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Henrich, T., Hirose, Y., Yasuoka, A., Yoda, H., Watanabe, T., Deguchi, T., Iwanami, N., Kunimatsu, S., Osakada, M., Loosli, F., Quiring, R., Carl, M., Grabher, C., Winkler, S., Del Bene, F., Wittbrodt, J., Abe, K., Takahama, Y., Takahashi, K., Katada, T., Nishina, H., Kondoh, H. and Furutani-Seiki, M. (2004). Mutations affecting somite formation in the Medaka (Oryzias latipes). Mech. Dev. 121, 659-671.

 

  • Kitagawa, D., Watanabe, T., Saito, K., Asaka, S., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Yasuoka, A., Deguchi, T., Yoda, H., Hirose, Y., Henrich, T., Iwanami, N., Kunimatsu, S., Osakada, M., Winkler, C., Elmasri, H., Wittbrodt, J., Loosli, F., Quiring, R., Carl, M., Grabher, C., Winkler, S., Del Bene, F., Momoi, A., Katada, T., Nishina, H., Kondoh, H. and Furutani-Seiki, M. (2004). Genetic dissection of the formation of the forebrain in Medaka, Oryzias latipes. Mech. Dev. 121, 673-685.

 

  • Loosli, F., Del Bene, F., Quiring, R., Rembold, M., Martinez-Morales, J.-R., Carl, M., Grabher, C., Iquel, C., Krone, A., Wittbrodt, B., Winkler, S., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Henrich, T., Deguchi, T., Hirose, Y., Iwanami, N., Kunimatsu, S., Osakada, M., Watanabe, T., Yasuoka, A., Yoda, H., Winkler, C., Elmasri, H., Kondoh, H., Furutani-Seiki, M. and Wittbrodt, J. (2004). Mutations affecting retina development in Medaka. Mech. Dev. 121, 703-714.

 

  • Watanabe, T., Asaka, S., Kitagawa, D., Saito, K., Kurashige, R., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Henrich, T., Hirose, Y., Yasuoka, A., Yoda, H., Deguchi, T., Iwanami, N., Kunimatsu, S., Osakada, M., Loosli, F., Quiring, R., Carl, M., Grabher, C., Winkler, S., Del Bene, F., Wittbrodt, J., Abe, K., Takahama, Y., Takahashi, K., Katada, T., Nishina, H., Kondoh, H. and Furutani-Seiki, M. (2004). Mutations affecting liver development and function in Medaka, Oryzias latipes, screened by multiple criteria. Mech. Dev. 121, 791-802.

 

  • Carl, M., Loosli, F. and Wittbrodt, J. (2002). Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye. Development 129, 4057- 4063.

 

  • Poggi, L., Carl, M., Vignali, R., Barsacchi, G. and Wittbrodt, J. (2002). Expression of a medaka (Oryzias latipes) Bar homologue in the differentiating central nervous system and retina. Mech. Dev. 114, 193-196.

 

  • Loosli, F., Winkler, S., Burgtorf, C., Wurmbach, E., Ansorge, W., Henrich, T., Grabher, C., Arendt, D., Carl, M., Krone, A., Grzebisz, E. and Wittbrodt, J. (2001). Medaka eyeless is the key factor linking retinal determination and eye growth. Development 128, 4035-4044.

 

  • Loosli, F., Koester, R.W., Carl, M., Kühnlein, R., Henrich, H., Mücke, M., Krone, A. and Wittbrodt, J. (2000). A genetic screen for mutations affecting embryonic development in medaka fish (Oryzias latipes). Mech. Dev. 97, 133-139.

 

  • Carl, M. and Wittbrodt, J. (1999). Graded interference with FGF-signalling reveals its dorso-ventral asymmetry at the mid-hindbrain boundary. Development 126, 5659- 5667.

 

  • Ristoratore, F., Carl, M., Deschet, K., Richard-Parpaillon, L., Boujard, D., Wittbrodt, J., Chourrout, D., Bourrat, F. and Joly, J.-S. (1999). The midbrain-hindbrain boundary genetic cascade is activated ectopically in the diencephalon in response to the widespread expression of one of its components, the medaka gene Ol-eng2. Development 126, 3769-3779.

 

  • Loosli, F., Koester, R.W., Carl, M., Krone, A. and Wittbrodt, J. (1998). Six3, a medaka homologue of the Drosophila homeobox gene sine oculis is expressed in the anterior embryonic shield and the developing eye. Mech. Dev. 74, 159-164.

PUBLICATIONS

bottom of page